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The four main components of blood are:
1. Red Blood Cells (RBCs) – The red, biconcave disc-shaped cell.
2. White Blood Cells (WBCs) – The grey, irregular-shaped cell with a nucleus.
3. Platelets – The small, fragment-like structures (orange/pink dots).
4. Plasma – The yellow fluid with a red sediment at the bottom (representing the liquid part of blood).
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| Component | Picture | Description | Function | Adaptations | Diseases |
|-------------------|--------|-----------------------------------------------------------------------------|--------------------------------------------------------------------------|------------------------------------------------------------------------------|---------------------------------------|
| Red Blood Cell | 🟧 | Biconcave disc-shaped cells without a nucleus; contain haemoglobin | Carry oxygen from lungs to tissues and carbon dioxide back to lungs | No nucleus → more space for haemoglobin; biconcave shape → increases surface area for gas exchange | Anaemia, Sickle cell disease |
| White Blood Cell | 🟨 | Irregular-shaped cells with a nucleus; larger than RBCs | Defend the body against infection (phagocytosis, antibody production) | Contains lots of ribosomes → protein synthesis for antibodies and enzymes | Leukaemia, AIDS |
| Platelets | 🟩 | Small, irregular fragments derived from megakaryocytes | Clotting of blood; prevent bleeding | Contain granules with clotting factors; sticky surface to adhere to damaged vessels | Thrombocytopenia, Haemophilia |
| Plasma | 🟫 | Yellowish fluid that makes up ~55% of blood; carries cells and substances | Transports hormones, nutrients, waste products, ions, proteins, gases | Contains water, dissolved substances, proteins (e.g., albumin, fibrinogen) | Dehydration, Liver disease, Kidney disease |
> Note: The picture in the last row shows plasma as a yellow liquid with a red layer at the bottom (which is likely representing the cellular components after centrifugation).
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#### 1. Suggest what the symptoms of anaemia might be?
Anaemia is caused by a deficiency in red blood cells or haemoglobin, leading to reduced oxygen delivery to tissues.
Symptoms:
- Fatigue and weakness
- Pale skin
- Shortness of breath
- Dizziness or lightheadedness
- Headaches
- Cold hands and feet
- Rapid or irregular heartbeat
> These occur because tissues don't get enough oxygen.
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#### 2. A normal white cell count is around 8500 cells per microliter. An AIDS sufferer has 680. Calculate the percentage decrease.
We use the formula:
$$
\text{Percentage decrease} = \left( \frac{\text{Original} - \text{New}}{\text{Original}} \right) \times 100
$$
$$
= \left( \frac{8500 - 680}{8500} \right) \times 100 = \left( \frac{7820}{8500} \right) \times 100 ≈ 91.94\%
$$
✔ Answer: Approximately 91.9% decrease
This shows a dramatic drop in immune function in AIDS patients.
---
#### 3. Explain why a white blood cell contains lots of ribosomes.
White blood cells (especially lymphocytes and phagocytes) are involved in producing:
- Antibodies (proteins)
- Enzymes for destroying pathogens
- Signaling molecules (cytokines)
Ribosomes are responsible for protein synthesis. Since WBCs need to make large amounts of these proteins, they have many ribosomes to support high levels of protein production.
✔ Answer: White blood cells contain many ribosomes because they produce large quantities of proteins like antibodies and enzymes to fight infections.
---
#### 4. The average lifespan of a red blood cell is 120 days. What makes new cells and where is it found?
- New red blood cells are made in the bone marrow.
- This process is called haematopoiesis.
- Specifically, hematopoietic stem cells in the bone marrow differentiate into red blood cells.
✔ Answer: New red blood cells are made by stem cells in the bone marrow, which is found inside the spongy bone of bones like the hip, spine, and skull.
---
| Component | Picture | Description | Function | Adaptations | Diseases |
|-------------------|--------|-----------------------------------------------------------------------------|--------------------------------------------------------------------------|------------------------------------------------------------------------------|---------------------------------------|
| Red Blood Cell | 🔴 | Biconcave disc, no nucleus, contains haemoglobin | Transport O₂ and CO₂ | No nucleus → more room for haemoglobin; biconcave shape → increased SA | Anaemia, Sickle cell disease |
| White Blood Cell | 🟡 | Larger, irregular, has nucleus | Fight infection (phagocytosis, antibodies) | Many ribosomes → protein synthesis | Leukaemia, AIDS |
| Platelets | 🟠 | Small fragments, no nucleus | Clotting (form clots to stop bleeding) | Sticky surface; contain clotting factors | Thrombocytopenia, Haemophilia |
| Plasma | 🟡 | Yellow fluid, carries cells and solutes | Transport nutrients, hormones, wastes, ions, gases | Contains water, proteins, ions | Dehydration, Liver/kidney disease |
---
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---
Step 1: Identify the 4 components of blood from the pictures
The four main components of blood are:
1. Red Blood Cells (RBCs) – The red, biconcave disc-shaped cell.
2. White Blood Cells (WBCs) – The grey, irregular-shaped cell with a nucleus.
3. Platelets – The small, fragment-like structures (orange/pink dots).
4. Plasma – The yellow fluid with a red sediment at the bottom (representing the liquid part of blood).
---
Step 2: Complete the table
| Component | Picture | Description | Function | Adaptations | Diseases |
|-------------------|--------|-----------------------------------------------------------------------------|--------------------------------------------------------------------------|------------------------------------------------------------------------------|---------------------------------------|
| Red Blood Cell | 🟧 | Biconcave disc-shaped cells without a nucleus; contain haemoglobin | Carry oxygen from lungs to tissues and carbon dioxide back to lungs | No nucleus → more space for haemoglobin; biconcave shape → increases surface area for gas exchange | Anaemia, Sickle cell disease |
| White Blood Cell | 🟨 | Irregular-shaped cells with a nucleus; larger than RBCs | Defend the body against infection (phagocytosis, antibody production) | Contains lots of ribosomes → protein synthesis for antibodies and enzymes | Leukaemia, AIDS |
| Platelets | 🟩 | Small, irregular fragments derived from megakaryocytes | Clotting of blood; prevent bleeding | Contain granules with clotting factors; sticky surface to adhere to damaged vessels | Thrombocytopenia, Haemophilia |
| Plasma | 🟫 | Yellowish fluid that makes up ~55% of blood; carries cells and substances | Transports hormones, nutrients, waste products, ions, proteins, gases | Contains water, dissolved substances, proteins (e.g., albumin, fibrinogen) | Dehydration, Liver disease, Kidney disease |
> Note: The picture in the last row shows plasma as a yellow liquid with a red layer at the bottom (which is likely representing the cellular components after centrifugation).
---
Step 3: Answer the Questions
#### 1. Suggest what the symptoms of anaemia might be?
Anaemia is caused by a deficiency in red blood cells or haemoglobin, leading to reduced oxygen delivery to tissues.
Symptoms:
- Fatigue and weakness
- Pale skin
- Shortness of breath
- Dizziness or lightheadedness
- Headaches
- Cold hands and feet
- Rapid or irregular heartbeat
> These occur because tissues don't get enough oxygen.
---
#### 2. A normal white cell count is around 8500 cells per microliter. An AIDS sufferer has 680. Calculate the percentage decrease.
We use the formula:
$$
\text{Percentage decrease} = \left( \frac{\text{Original} - \text{New}}{\text{Original}} \right) \times 100
$$
$$
= \left( \frac{8500 - 680}{8500} \right) \times 100 = \left( \frac{7820}{8500} \right) \times 100 ≈ 91.94\%
$$
✔ Answer: Approximately 91.9% decrease
This shows a dramatic drop in immune function in AIDS patients.
---
#### 3. Explain why a white blood cell contains lots of ribosomes.
White blood cells (especially lymphocytes and phagocytes) are involved in producing:
- Antibodies (proteins)
- Enzymes for destroying pathogens
- Signaling molecules (cytokines)
Ribosomes are responsible for protein synthesis. Since WBCs need to make large amounts of these proteins, they have many ribosomes to support high levels of protein production.
✔ Answer: White blood cells contain many ribosomes because they produce large quantities of proteins like antibodies and enzymes to fight infections.
---
#### 4. The average lifespan of a red blood cell is 120 days. What makes new cells and where is it found?
- New red blood cells are made in the bone marrow.
- This process is called haematopoiesis.
- Specifically, hematopoietic stem cells in the bone marrow differentiate into red blood cells.
✔ Answer: New red blood cells are made by stem cells in the bone marrow, which is found inside the spongy bone of bones like the hip, spine, and skull.
---
✔ Final Summary Table:
| Component | Picture | Description | Function | Adaptations | Diseases |
|-------------------|--------|-----------------------------------------------------------------------------|--------------------------------------------------------------------------|------------------------------------------------------------------------------|---------------------------------------|
| Red Blood Cell | 🔴 | Biconcave disc, no nucleus, contains haemoglobin | Transport O₂ and CO₂ | No nucleus → more room for haemoglobin; biconcave shape → increased SA | Anaemia, Sickle cell disease |
| White Blood Cell | 🟡 | Larger, irregular, has nucleus | Fight infection (phagocytosis, antibodies) | Many ribosomes → protein synthesis | Leukaemia, AIDS |
| Platelets | 🟠 | Small fragments, no nucleus | Clotting (form clots to stop bleeding) | Sticky surface; contain clotting factors | Thrombocytopenia, Haemophilia |
| Plasma | 🟡 | Yellow fluid, carries cells and solutes | Transport nutrients, hormones, wastes, ions, gases | Contains water, proteins, ions | Dehydration, Liver/kidney disease |
---
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