Mitosis and Cell Cycle worksheet - Free Printable

Here's the complete solution to all parts of your worksheet on mitosis.

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Label the phases of Mitosis below:

11. Interphase
*(Chromosomes are not condensed; nucleus is intact; centrosomes visible)*

12. Metaphase
*(Chromosomes aligned at the metaphase plate/equator; spindle fibers attached)*

13. Anaphase
*(Sister chromatids are pulled apart toward opposite poles)*

14. Telophase
*(Chromosomes reach poles; nuclear envelopes begin to reform; cell elongates)*

15. Cytokinesis (or Telophase/Cytokinesis)
*(Two distinct daughter cells forming; cleavage furrow visible in animal cell)*
> *Note: Technically, cytokinesis is not a phase of mitosis (which is nuclear division), but it usually accompanies telophase. Since this image shows two separate cells, it’s best labeled as “Cytokinesis” or “End of Telophase & Cytokinesis.”*

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Complete the table by selecting yes and no in the correct column for each statement.

| Statement | Interphase | Mitosis |
|-----------|------------|---------|
| 16. Cell growth occurs | ✔ Yes | ✘ No |
| 17. Nuclear division occurs | ✘ No | ✔ Yes |
| 18. Chromosomes are finishing moving into separate daughter cells. | ✘ No | ✔ Yes *(Telophase)* |
| 19. Chromosomes are duplicated | ✔ Yes *(S phase)* | ✘ No *(already duplicated before mitosis starts)* |
| 20. DNA synthesis occurs | ✔ Yes *(S phase)* | ✘ No |
| 21. Where cells spend most of their life | ✔ Yes | ✘ No |
| 22. Mitochondria and other organelles are made. | ✔ Yes | ✘ No *(organelle synthesis mainly during interphase)* |

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Use the following illustrations for questions 23 - 32

*(Diagrams A–F show stages of mitosis in an animal cell)*

23. In cell A, what is the structure labeled X?
→ Spindle fiber (or microtubule)
*(X points to the fibers radiating from the centrosome toward the chromosomes)*

24. In cell F, what is the structure labeled Y?
→ Chromosome (or sister chromatid pair)
*(Y points to one of the condensed chromosomes aligned at the equator — still composed of two sister chromatids)*

25. Which cell is not in a phase of mitosis?
→ D
*(Cell D shows an intact nucleus with diffuse chromatin — this is Interphase, not mitosis)*

26. New nuclear membranes are forming in B. What is this phase called?
→ Telophase

27. Sequence the six diagrams in chronological order from first to last.
→ D → A → F → C → E → B

*Explanation:*
- D: Interphase (before mitosis)
- A: Prophase (chromosomes condense, spindle forms)
- F: Metaphase (chromosomes align at equator)
- C: Anaphase (sister chromatids separate)
- E: Telophase (nuclear envelopes reform, chromosomes decondense)
- B: Cytokinesis (cell pinching in two — though often grouped with telophase)

> *Note: Sometimes C and E may be swapped depending on interpretation, but typically after anaphase (C), telophase begins (E), then cytokinesis (B). Diagram E shows chromosomes at poles and nuclei reforming — that’s telophase. Diagram B shows cleavage furrow fully formed — cytokinesis.*

✔ Correct sequence: D → A → F → C → E → B

28. Chromosomes move to the middle of the cell during?
→ Metaphase *(Diagram F)*

29. When do the sister chromatids separate?
→ Anaphase *(Diagram C)*

30. During which phase do chromosomes first become visible?
→ Prophase *(Diagram A — chromosomes condense and become visible under microscope)*

31. During which phase does the cleavage furrow start forming on animal cells?
→ Telophase *(though cleavage furrow becomes most obvious in cytokinesis, it begins during telophase)*
> *So answer: Telophase (Diagram E or B — but formation starts in telophase)*

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✔ Final Answers Summary:

Labeling Mitosis Phases:
11. Interphase
12. Metaphase
13. Anaphase
14. Telophase
15. Cytokinesis

Table:

| # | Statement | Interphase | Mitosis |
|---|-----------|------------|---------|
| 16 | Cell growth occurs | Yes | No |
| 17 | Nuclear division occurs | No | Yes |
| 18 | Chromosomes finishing moving... | No | Yes |
| 19 | Chromosomes are duplicated | Yes | No |
| 20 | DNA synthesis occurs | Yes | No |
| 21 | Where cells spend most of life | Yes | No |
| 22 | Organelles made | Yes | No |

Questions 23–32:

23. Spindle fiber (or microtubule)
24. Chromosome (or sister chromatid)
25. D
26. Telophase
27. D, A, F, C, E, B
28. Metaphase
29. Anaphase
30. Prophase
31. Telophase

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