Worksheet illustrating DNA mutations and their effects on protein sequences, focusing on sickle cell anemia.

Let’s solve this step by step.

We are given a math problem that looks like this:

```
82
+ 39
-----
```

This is an addition problem. We need to add 82 and 39 together.

Step 1: Add the ones place (the rightmost digits).
- 2 (from 82) + 9 (from 39) = 11
- Write down the 1 in the ones place of the answer.
- Carry over the other 1 to the tens place (because 11 is 1 ten and 1 one).

Step 2: Add the tens place, including the carried-over 1.
- 8 (from 82) + 3 (from 39) = 11
- Plus the 1 we carried over → 11 + 1 = 12
- Write down 12 in the tens and hundreds places.

So putting it together:
- The ones digit is 1.
- The tens and hundreds digits are 12.

That gives us 121.

Let’s double-check:
82 + 39
= 80 + 2 + 30 + 9
= (80 + 30) + (2 + 9)
= 110 + 11
= 121 ✔

Final Answer:
121