1. The trait is autosomal recessive.
2. In Generation I: Individual 2 (female) and Individual 4 (female) are carriers.
In Generation II: Individual 2 (female), Individual 3 (male), and Individual 6 (female) are carriers.
3. We cannot determine who are carriers in generation III because unaffected individuals in a recessive pedigree can be either homozygous dominant or heterozygous carriers, and without genetic testing or more offspring data, we cannot distinguish between them.
4. The second-generation children inherited sickle cell anemia from both parents, as it is a recessive trait requiring two copies of the allele.
5. [recessive]
Parent Tip: Review the logic above to help your child master the concept of pedigree problems worksheet.