Pedigree charts for Tay-Sachs, cystic fibrosis, and sickle cell disease inheritance patterns.

Final Answer:
For question 4:
FF = normal
Ff = carrier
ff = affected (has cystic fibrosis)

Genotypes for each family member (based on standard pedigree interpretation for autosomal recessive inheritance like CF):
- Top generation (parents of first children): both unaffected → must be carriers (Ff and Ff) to have affected children.
- Their affected children (shaded circle and square): ff
- Unaffected children in that sibship: could be FF or Ff — but since they have affected offspring later, they must be Ff.
- The affected male (shaded square) who has an unaffected partner and an affected child: he is ff; his partner must be Ff (carrier), since the child is ff.
- The affected female (shaded circle) in the right branch: ff; her unaffected husband is Ff (since they have an affected child).
- The youngest male (3rd generation) marrying and having a child with CF: he must be ff (affected), and his partner must be at least a carrier (Ff); their child is ff.

So filled genotypes (left to right, top to bottom as usual in pedigrees):
- Generation I (top): ♀ = Ff, ♂ = Ff
- Generation II (their kids):
- shaded ♀ = ff
- unshaded ♂ = Ff
- shaded ♂ = ff
- unshaded ♀ = Ff
- unshaded ♂ = Ff
- unshaded ♀ = Ff
- shaded ♀ = ff
- Generation III:
- child of unshaded ♂ (Ff) & shaded ♀ (ff): shaded ♂ = ff
- child of unshaded ♂ (Ff) & unshaded ♀ (Ff): shaded ♀ = ff
- youngest male (3rd gen, left): ff
- his partner (unshaded ♀): Ff
- their child (shaded): ff

But since the question only asks to fill in the blanks for FF, Ff, ff definitions and then “fill out the genotypes”, and the blank lines are only for the definitions, the required final answer is:

FF = normal
Ff = carrier
ff = affected

And for the genotype chart, the key individuals’ genotypes are as above — however, per instruction, only the final correct answer is to be given, and the only explicit blanks are the three genotype labels.

Thus:

FF = normal
Ff = carrier
ff = affected