Karyotype Worksheet 1 | PDF | Karyotype | Cell Nucleus - Free Printable

Since I cannot view or process images directly — including karyotype diagrams — I’ll provide you with a complete, step-by-step guide to solving this type of karyotype analysis worksheet based on standard biology curriculum content. This will allow you to solve the problem yourself using the image you uploaded.

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## 🔍 Step-by-Step Guide to Solving Karyotype Analysis Questions

📌 Question 4: “Look at the karyotype to the right. Do you see any chromosomal abnormalities? Yes / No”

✔ How to answer:
- A normal human karyotype has 46 chromosomes: 22 pairs of autosomes + 1 pair of sex chromosomes (XX for female, XY for male).
- Look for:
- Extra chromosomes (trisomy)
- Missing chromosomes (monosomy)
- Structural abnormalities (deletions, translocations — less common in basic worksheets)
- If all chromosomes are in pairs and number 46, answer No.
- If there’s an extra chromosome (e.g., three copies of chromosome 21), answer Yes.

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📌 Question 5: “Put a star around the abnormal chromosomes.”

✔ How to do it:
- Identify which chromosome is not in a pair (e.g., chromosome 21 appears 3 times → trisomy 21).
- Circle or star that chromosome pair (or trio) in your image.

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📌 Question 6: “Using the key below for chromosomal disorders, identify the disease this person has.”

✔ Use the provided key:

| Chromosome Problem | Name of Disorder |
|--------------------|--------------------------|
| XXX | Turner’s Syndrome |
| XXY | Triple X Disease |
| XYY | Jacob’s Syndrome |
| Trisomy 21 | Down’s Syndrome |
| Trisomy 18 | Edwards’ Syndrome |
| Trisomy 13 | Patau Syndrome |

> ❗️Note: There’s a mistake in the key — XXX is NOT Turner’s Syndrome.
> - Turner’s Syndrome = XO (only one X, no second sex chromosome)
> - Triple X = XXX (three X chromosomes in females)
> - Klinefelter’s = XXY (male with extra X)
> - Jacob’s = XYY (male with extra Y)

So if the karyotype shows:
- Three copies of chromosome 21 → Down’s Syndrome
- XXY → Klinefelter’s Syndrome (but listed as “Triple X Disease” — incorrect)
- XO → Turner’s Syndrome (not listed correctly)

➡️ Match what you see in the karyotype to the disorder names as given in the worksheet, even if they’re mislabeled.

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📌 Question 7: “Is this person male or female?”

✔ How to tell:
- Look at the last pair of chromosomes (sex chromosomes):
- XX → Female
- XY → Male

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📌 Question 8: “NORMAL or ABNORMAL?”

✔ Answer:
- If all 46 chromosomes are present and paired → NORMAL
- If any extra/missing chromosome → ABNORMAL

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📌 Question 9: “Using the key above, what disease does this karyotype have?”

✔ Same as Q6 — match the abnormality to the disorder name in the key.

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📌 Question 10: “Which chromosome is the largest and has the most genes?”

✔ Answer: Chromosome 1
→ It’s the largest human chromosome and carries the most genes (~2,000–3,000).

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📌 Question 11: “Which chromosome is the shortest and has the fewest genes?”

✔ Answer: Chromosome 21 (or sometimes 22 — but 21 is often cited as smallest autosome)
→ Has the fewest genes (~200–300).
*(Note: Chromosome 21 is the smallest autosome; the Y chromosome is smaller but is a sex chromosome.)*

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📌 Question 12: “In a normal karyotype, how many autosomal chromosomes are there?”

✔ Answer: 44
→ Autosomes = chromosomes 1–22 → 22 pairs = 44 chromosomes.
→ Sex chromosomes (XX or XY) = 2 chromosomes → total 46.

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📌 Question 13: “In a normal karyotype, how many sex chromosomes are there? What is another name for them?”

✔ Answer:
- 2 sex chromosomes (either XX or XY)
- Another name: Allosomes (less commonly used term in high school bio — usually just called “sex chromosomes”)

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## ✔ Example Solution (Assuming Common Case: Down’s Syndrome)

Let’s say your karyotype shows three copies of chromosome 21:

- Q4: Yes (abnormality present)
- Q5: Star the three chromosome 21s
- Q6 & Q9: Down’s Syndrome
- Q7: Could be male or female — check sex chromosomes (e.g., if XY → male)
- Q8: ABNORMAL
- Q10: Chromosome 1
- Q11: Chromosome 21
- Q12: 44
- Q13: 2; sex chromosomes

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## 🧠 Pro Tip:
If you can describe what you see in the karyotype (e.g., “There are 3 copies of chromosome 21, and the sex chromosomes are XY”), I can give you the exact answers!

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## 🚫 Important Note About the Worksheet Key:

The table contains errors:
- XXX ≠ Turner’s Syndrome → That’s XO
- XXY ≠ Triple X → That’s Klinefelter’s Syndrome
- Triple X = XXX
- Jacob’s = XYY

If your teacher expects you to use the worksheet’s key *as written*, then follow it — even if it’s wrong. But scientifically, here’s the correct mapping:

| Chromosome Abnormality | Correct Disorder Name |
|------------------------|----------------------------|
| XO | Turner’s Syndrome |
| XXX | Triple X Syndrome |
| XXY | Klinefelter’s Syndrome |
| XYY | Jacob’s Syndrome |
| Trisomy 21 | Down’s Syndrome |
| Trisomy 18 | Edwards’ Syndrome |
| Trisomy 13 | Patau Syndrome |

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## 📝 Final Answer Summary (Fill-in-the-blank Style):

*(Assuming a typical Down’s Syndrome karyotype with XY)*

4. ✔ Yes
5. ⭐ Star the three chromosome 21s
6. ✔ Down’s Syndrome
7. ✔ Male (if XY) or Female (if XX)
8. ✔ ABNORMAL
9. ✔ Down’s Syndrome
10. ✔ Chromosome 1
11. ✔ Chromosome 21
12. ✔ 44
13. ✔ 2; sex chromosomes

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📌 If you can describe the karyotype (e.g., “chromosome 21 has 3 copies, sex chromosomes are XX”), I’ll give you the exact answers tailored to your image!

Let me know if you want to upload a description or text version of the karyotype!