- Year: 1325
Event: The Aztecs founded Tenochtitlan on an island in Lake Texcoco after seeing an eagle perched on a cactus, which was their prophesied sign.
- Year: 1428
Event: The Aztecs formed the Triple Alliance with the city-states of Texcoco and Tlacopan, marking the beginning of the Aztec Empire.
- Year: 1440
Event: Moctezuma I became the second emperor (huey tlatoani) and expanded the empire through military conquests.
- Year: 1486
Event: Ahuitzotl became emperor and significantly expanded the empire’s territory to its greatest extent.
- Year: 1502
Event: Moctezuma II ascended the throne, ruling during the arrival of the Spanish conquistadors.
- Year: 1519
Event: Hernán Cortés and his Spanish forces landed in Mexico and began their march toward Tenochtitlan.
- Year: 1520
Event: The Spanish were temporarily driven out of Tenochtitlan during the “Noche Triste,” but returned later that year.
- Year: 1521
Event: The Spanish, with indigenous allies, besieged and captured Tenochtitlan, leading to the fall of the Aztec Empire.
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